Occupational exposure and risk of breast cancer
Identifieur interne : 000020 ( Main/Exploration ); précédent : 000019; suivant : 000021Occupational exposure and risk of breast cancer
Auteurs : Concettina Fenga [Italie]Source :
- Biomedical Reports [ 2049-9434 ] ; 2016.
Abstract
Breast cancer is a multifactorial disease and the most commonly diagnosed cancer in women. Traditional risk factors for breast cancer include reproductive status, genetic mutations, family history and lifestyle. However, increasing evidence has identified an association between breast cancer and occupational factors, including environmental stimuli. Epidemiological and experimental studies demonstrated that ionizing and non-ionizing radiation exposure, night-shift work, pesticides, polycyclic aromatic hydrocarbons and metals are defined environmental factors for breast cancer, particularly at young ages. However, the mechanisms by which occupational factors can promote breast cancer initiation and progression remains to be elucidated. Furthermore, the evaluation of occupational factors for breast cancer, particularly in the workplace, also remains to be explained. The present review summarizes the occupational risk factors and the associated mechanisms involved in breast cancer development, in order to highlight new environmental exposures that could be correlated to breast cancer and to provide new insights for breast cancer prevention in the occupational settings. Furthermore, this review suggests that there is a requirement to include, through multidisciplinary approaches, different occupational exposure risks among those associated with breast cancer development. Finally, the design of new epigenetic biomarkers may be useful to identify the workers that are more susceptible to develop breast cancer.
Url:
DOI: 10.3892/br.2016.575
PubMed: 26998264
PubMed Central: 4774377
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000045
- to stream Pmc, to step Curation: 000045
- to stream Pmc, to step Checkpoint: 000016
- to stream Ncbi, to step Merge: 000445
- to stream Ncbi, to step Curation: 000445
- to stream Ncbi, to step Checkpoint: 000445
- to stream Main, to step Merge: 000020
- to stream Main, to step Curation: 000020
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Occupational exposure and risk of breast cancer</title>
<author><name sortKey="Fenga, Concettina" sort="Fenga, Concettina" uniqKey="Fenga C" first="Concettina" last="Fenga">Concettina Fenga</name>
<affiliation wicri:level="1"><nlm:aff id="af1-br-0-0-575">Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Occupational Medicine Section, ‘Policlinico G. Martino’ Hospital, University of Messina, Messina I-98125, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Occupational Medicine Section, ‘Policlinico G. Martino’ Hospital, University of Messina, Messina I-98125</wicri:regionArea>
<wicri:noRegion>Messina I-98125</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">26998264</idno>
<idno type="pmc">4774377</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774377</idno>
<idno type="RBID">PMC:4774377</idno>
<idno type="doi">10.3892/br.2016.575</idno>
<date when="2016">2016</date>
<idno type="wicri:Area/Pmc/Corpus">000045</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000045</idno>
<idno type="wicri:Area/Pmc/Curation">000045</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000045</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000016</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000016</idno>
<idno type="wicri:Area/Ncbi/Merge">000445</idno>
<idno type="wicri:Area/Ncbi/Curation">000445</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000445</idno>
<idno type="wicri:doubleKey">2049-9434:2016:Fenga C:occupational:exposure:and</idno>
<idno type="wicri:Area/Main/Merge">000020</idno>
<idno type="wicri:Area/Main/Curation">000020</idno>
<idno type="wicri:Area/Main/Exploration">000020</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Occupational exposure and risk of breast cancer</title>
<author><name sortKey="Fenga, Concettina" sort="Fenga, Concettina" uniqKey="Fenga C" first="Concettina" last="Fenga">Concettina Fenga</name>
<affiliation wicri:level="1"><nlm:aff id="af1-br-0-0-575">Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Occupational Medicine Section, ‘Policlinico G. Martino’ Hospital, University of Messina, Messina I-98125, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Occupational Medicine Section, ‘Policlinico G. Martino’ Hospital, University of Messina, Messina I-98125</wicri:regionArea>
<wicri:noRegion>Messina I-98125</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Biomedical Reports</title>
<idno type="ISSN">2049-9434</idno>
<idno type="eISSN">2049-9442</idno>
<imprint><date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Breast cancer is a multifactorial disease and the most commonly diagnosed cancer in women. Traditional risk factors for breast cancer include reproductive status, genetic mutations, family history and lifestyle. However, increasing evidence has identified an association between breast cancer and occupational factors, including environmental stimuli. Epidemiological and experimental studies demonstrated that ionizing and non-ionizing radiation exposure, night-shift work, pesticides, polycyclic aromatic hydrocarbons and metals are defined environmental factors for breast cancer, particularly at young ages. However, the mechanisms by which occupational factors can promote breast cancer initiation and progression remains to be elucidated. Furthermore, the evaluation of occupational factors for breast cancer, particularly in the workplace, also remains to be explained. The present review summarizes the occupational risk factors and the associated mechanisms involved in breast cancer development, in order to highlight new environmental exposures that could be correlated to breast cancer and to provide new insights for breast cancer prevention in the occupational settings. Furthermore, this review suggests that there is a requirement to include, through multidisciplinary approaches, different occupational exposure risks among those associated with breast cancer development. Finally, the design of new epigenetic biomarkers may be useful to identify the workers that are more susceptible to develop breast cancer.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>Italie</li>
</country>
</list>
<tree><country name="Italie"><noRegion><name sortKey="Fenga, Concettina" sort="Fenga, Concettina" uniqKey="Fenga C" first="Concettina" last="Fenga">Concettina Fenga</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Terre/explor/CobaltMaghrebV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000020 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000020 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Terre |area= CobaltMaghrebV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:4774377 |texte= Occupational exposure and risk of breast cancer }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:26998264" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a CobaltMaghrebV1
This area was generated with Dilib version V0.6.32. |